Discoveries
Objevy Alexandra Fleminga
Život Alexandra Fleminga byl plný neuvěřitelných okolností, náhod, a objevů, díky kterým se stal posléze světoznámým, uznávaným mikrobiologem a bakteriologem. Jeho úspěšná vědecká kariéra započala už před První světovou válkou, ve které se vyznamenal na poli chirurgie, pokračovala v meziválečném období, ve kterém se uskutečnily jeho nejvýznamnější pokusy a byla zakončena ziskem Nobelovy ceny a pasováním do šlechtického stavu Sir.
Objevy v mládí
Jak už bylo zmíněno v úvodu, život Fleminga byl samá náhoda. Po ukončení lékařské fakulty byl vystudovaný chirurg, ale díky profesorům Wrightovi a Freemanovi, který si ho vybral pro jeho talent, ne v bakteriologii, ale ve střelbě, se stal mladý Alexandr součástí laboratoře, ve které působil celý život. První větší úspěch bylo stanovení prvotních příznaků tuberkulózy, čímž si laboratoř zajistila jméno a příjmy. Toto velice slibné období ukončila Světová válka.
První světová válka
Flemingovo jméno se během Světové války zviditelnilo opět díky profesoru Wrightovi. Wright byl nasazen v laboratoři, která působila na území Francie. S sebou si povolal i Freemana s Flemingem. Zde se projevil Fleming jako chirurg, když začal praktikovat odebírání poškozené tkáně, aby se zabránilo infekci nebo jejímu případnému šíření. Profesor Wright zde dokázal, že ke zničení mikrobů je třeba zavést do rány hypertonický roztok soli, který zvyšuje odtok lymfy z těla. Dalším významným počinem této laboratoře bylo zjištění, že prostředky, kterými se sterilizovali chirurgické nástroje, jsou nedostačují, ba dokonce napomáhají růstu a životu bakterií. Tyto poznatky byli důležité pro další rozvoj chirurgie.
Objev lysozymu
K tomuto objevu došlo v roce 1922. Fleming vzal nosní hlen a umístil ho do Petriho misky, ve které byli už předtím kolonie mikroorganismů, které následně uhynuly. To samé se stalo, když umístil do misky slzu. Proto se rozhodl zkoumat slzy a nalezl enzym, který pojmenoval lysozym. Během dalších pozorování zjistil, že lysozym nezabíjí všechny mikroorganismy, ale pouze ty neškodné. Ovšem Fleminga napadlo, že lysozym vlastně určuje, které mikroorganismy jsou patogenní. Bakterie povětšinou zabíjel lysozym obsažený ve vaječném bílku, který ovšem nikdo neuměl oddělit. Proto pokus probíhal aplikací ředěného bílku nitrožilně králíkovi. Pokusy byly úspěšné, ale příliš náročné na tehdejší dobu.
Lysozym (lysis-zředěný) je enzym, který se vyskytuje v lidském těle nebo vaječném bílku. Má silné antibakteriální účinky, které narušují buněčné stěny bakterií.
Objev penicilinu
Je známo, že největší objevy a vynálezy vznikly a vznikají náhodou. Ne jinak tomu bylo v roce 1928 kdy, se přepsala historie medicíny, aniž by to kdokoliv v té době věděl nebo snad jenom tušil. Alexander Fleming toho dne vešel do laboratoře, kde byla zapomenutá Petriho miska, ve které byl agar (živná směs z červených řas, ve které se pěstují mikroorganismy), na něm byla plíseň. A právě v tento okamžik objevil Fleming antibiotickou účinnost penicilinu, konkrétně to byla houba Penicillium notatu. Látky, které uvolňovala, zabíjely většinu bakterií, kromě těch, které způsobují tyfus. Tento jev byl sice už známý, ale nikomu se ho nepodařilo provést laboratorně s takovým úspěchem. Aby mohli i nadále pozorovat penicilin, pěstoval se v masovém vývaru o teplotě 37⁰C. Po poradě s mykology byla tato teplota snížena na 20⁰C. Vzniklý vývar opravdu fungoval, zabíjel škodlivé bakterie a neškodil fagocytům (buňka, která je schopná pohlcovat pevné částice skrz membránu). Tento produkt fungoval při zředění, ale vydržel jen krátkou dobu. Zásadní problémem bylo že, nikdo neuměl oddělit tuto látku a vývar jako takový byl v medicíně nepoužitelný. Ačkoliv Fleming svůj objev publikoval mezi ostatní vědce, nikdo nejevil o jeho objev zájem.
Vše se změnilo v roce 1940 chemikovi Ernstu Chainovi a biochemikovi Howardu Floreymu. Brzy se začalo s testováním na zvířatech, které bylo více než uspokojivé. V únoru 1941 byl poprvé podán lék člověku, který umíral. Pro nedostatek látky pacient zemřel, ale léčivá účinnost penicilinu byla prokázána i na lidech. Po dostatečném nashromáždění zásob, byl penicilin podán dalším třem lidem. Dva pacienti se úspěšně uzdravili, třetí zemřel na komplikace.
Naneštěstí pro Fleminga i společnost se tyto převratné objevy odehrály během Druhé světové války. Nikdo si nemohl dovolit zafinancovat výrobu léčiva, která by byla prodělečná. Proto se Florey rozhodl odjet do USA, kde se pokusili vypěstovat penicilin na kukuřici, ale to se nezdařilo. Jediným úspěchem byl plesnivý meloun, který se stal základem na výrobu penicilinu v USA a prvních deseti tisíců litrů. Z této kultury vznikly i všechny ostatních, na kterých se vyrábí penicilin dodnes. V roce 1942 se rozšířila zpráva o novém léku a o rok později už se o něj zajímali farmaceutické společnosti. Tento objev vynesl pánům Chainovi, Floreymu a Flemingovi Nobelu cenu, kterou obdrželi 25.10.1945.
Sir Alexander Fleming byl za svůj bohatý život ověnčen mnoha oceněními a zásluhami. On sám však sebe považoval vždy za člověka náhod. A jak už bylo mnohokrát řečeno, tohoto velikána medicíny doprovázela náhoda na každém kroku. A za to jsme vděčni.
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Technology and AI news
(Technology_xusl, 2. 8. 2023 20:21)
Opportunities and Risks of Artificial Intelligence
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The Basic Principles Of jewish killers
(EeugeneTrinc, 1. 8. 2023 0:43)
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https://russiawithoutborders.com
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(Williamhef, 31. 7. 2023 7:58)
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線上賭場
(AngelHic, 27. 7. 2023 3:55)
線上賭場
彩票是一種稱為彩券的憑證，上面印有號碼圖形或文字，供人們填寫、選擇、購買，按照特定的規則取得中獎權利。彩票遊戲在兩個平台上提供服務，分別為富游彩票和WIN539，這些平台提供了539、六合彩、大樂透、台灣彩券、美國天天樂、威力彩、3星彩等多種選擇，使玩家能夠輕鬆找到投注位置，這些平台在操作上非常簡單。
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另一種受歡迎的博彩遊戲是電子遊戲，也被稱為老虎機或角子機。這些遊戲簡單易上手，是賭場裡最受歡迎的遊戲之一，新手玩家也能輕鬆上手。遊戲的目的是使相同的圖案排列成形，就有機會贏取獎金。不同的遊戲有不同的規則和組合方式，刮刮樂、捕魚機、老虎機等都是電子遊戲的典型代表。
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娛樂城為了吸引玩家，提供了各種優惠活動。新會員可以選擇不同的好禮，如體驗金、首存禮等，還有會員專區和VIP特權福利等多樣的優惠供玩家選擇。為了方便玩家存取款，線上賭場提供各種存款方式，包括各大銀行轉帳/ATM轉帳儲值和超商儲值等。
總的來說，彩票、棋牌遊戲、電子遊戲、電競遊戲和捕魚遊戲等是多樣化的娛樂方式，它們滿足了不同玩家的需求和喜好。這些娛樂遊戲也提供了豐富的優惠活動，吸引玩家參與並享受其中的樂趣。如果您喜歡娛樂和遊戲，這些娛樂方式絕對是您的不二選擇
線上賭場
(AngelHic, 25. 7. 2023 22:09)
線上賭場
彩票是一種稱為彩券的憑證，上面印有號碼圖形或文字，供人們填寫、選擇、購買，按照特定的規則取得中獎權利。彩票遊戲在兩個平台上提供服務，分別為富游彩票和WIN539，這些平台提供了539、六合彩、大樂透、台灣彩券、美國天天樂、威力彩、3星彩等多種選擇，使玩家能夠輕鬆找到投注位置，這些平台在操作上非常簡單。
彩票的種類非常多樣，包括539、六合彩、大樂透、台灣彩券、美國天天樂、威力彩和3星彩等。
除了彩票，棋牌遊戲也是一個受歡迎的娛樂方式，有兩個主要平台，分別是OB棋牌和好路棋牌。在這些平台上，玩家可以與朋友聯繫，進行對戰。在全世界各地，撲克和麻將都有自己獨特的玩法和規則，而棋牌遊戲因其普及、易上手和益智等特點，而受到廣大玩家的喜愛。一些熱門的棋牌遊戲包括金牌龍虎、百人牛牛、二八槓、三公、十三隻、炸金花和鬥地主等。
另一種受歡迎的博彩遊戲是電子遊戲，也被稱為老虎機或角子機。這些遊戲簡單易上手，是賭場裡最受歡迎的遊戲之一，新手玩家也能輕鬆上手。遊戲的目的是使相同的圖案排列成形，就有機會贏取獎金。不同的遊戲有不同的規則和組合方式，刮刮樂、捕魚機、老虎機等都是電子遊戲的典型代表。
除此之外，還有一種娛樂方式是電競遊戲，這是一種使用電子遊戲進行競賽的體育項目。這些電競遊戲包括虹彩六號：圍攻行動、英雄聯盟、傳說對決、PUBG、皇室戰爭、Dota 2、星海爭霸2、魔獸爭霸、世界足球競賽、NBA 2K系列等。這些電競遊戲都是以勝負對戰為主要形式，受到眾多玩家的熱愛。
捕魚遊戲也是一種受歡迎的娛樂方式，它在大型平板類遊戲機上進行，多人可以同時參與遊戲。遊戲的目的是擊落滿屏的魚群，通過砲彈來打擊不同種類的魚，玩家可以操控自己的炮臺來獲得獎勵。捕魚遊戲的獎金將根據捕到的魚的倍率來計算，遊戲充滿樂趣和挑戰，也有一些變化，例如打地鼠等。
娛樂城為了吸引玩家，提供了各種優惠活動。新會員可以選擇不同的好禮，如體驗金、首存禮等，還有會員專區和VIP特權福利等多樣的優惠供玩家選擇。為了方便玩家存取款，線上賭場提供各種存款方式，包括各大銀行轉帳/ATM轉帳儲值和超商儲值等。
總的來說，彩票、棋牌遊戲、電子遊戲、電競遊戲和捕魚遊戲等是多樣化的娛樂方式，它們滿足了不同玩家的需求和喜好。這些娛樂遊戲也提供了豐富的優惠活動，吸引玩家參與並享受其中的樂趣。如果您喜歡娛樂和遊戲，這些娛樂方式絕對是您的不二選擇
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The Future of Artificial Intelligence: Beauty and Possibilities
In the coming decades, there will be a time when artificial intelligence will create stunning ladies using a printer developed by scientists working with DNA technologies, artificial insemination, and cloning. The beauty of these ladies will be unimaginable, allowing each individual to fulfill their cherished dreams and create their ideal life partner.
Advancements in artificial intelligence and biotechnology over the past decades have had a profound impact on our lives. Each day, we witness new discoveries and revolutionary technologies that challenge our understanding of the world and ourselves. One such awe-inspiring achievement of humanity is the ability to create artificial beings, including beautifully crafted women.
The key to this new era lies in artificial intelligence (AI), which already demonstrates incredible capabilities in various aspects of our lives. Using deep neural networks and machine learning algorithms, AI can process and analyze vast amounts of data, enabling it to create entirely new things.
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Introduction
In recent years, the field of artificial intelligence has witnessed tremendous advancements in image generation, thanks to the application of neural networks. Among these marvels is the remarkable ability of neural networks to draw dogs and create stunningly realistic artwork. This article delves into the fascinating world of how neural networks, specifically Generative Adversarial Networks (GANs) and Deep Convolutional Neural Networks (DCGANs), are employed to generate awe-inspiring images of our four-legged friends.
The Power of Generative Adversarial Networks (GANs)
Generative Adversarial Networks (GANs) are a class of artificial intelligence models consisting of two neural networks - the generator and the discriminator. The generator is responsible for creating images, while the discriminator's role is to distinguish between real and generated images. The two networks are pitted against each other in a "game," where the generator aims to produce realistic images that can fool the discriminator, while the discriminator endeavors to become more adept at recognizing real images from the generated ones.
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